CONTACT INFO

Gilad Silberberg, Nobel Institute for Neurophysiology, Department of Neuroscience, Karolinska Institutet, SE-17177 Stockholm, Sweden.
Tel: +46 8 5248 7886/7086
Fax: +46 8 349544
Email: gilad.silberberg@neuro.ki.se
http://www.neuro.ki.se/silberberg

RESEARCH INTERESTS

My primary interest is to understand various sensory-motor processes, by studying the structural and functional properties of the underlying neuronal microcircuits. The regions of interest are the neocortex and basal ganglia, and the synaptic connections between these brain areas. The techniques used include whole-cell patch clamp recordings from multiple neurons in vitro and in vivo, dendritic patch-recordings, 3D morphological reconstructions of recorded neurons, as well as computational modeling to explore and capture key information processing steps.

POSITIONS

2005: HFSP Long-Term Fellowship at the lab of Sten Grillner , Nobel institute for Neurophysiology.

2002 – 2004: Electrophysiology group-leader in the Laboratory of Neural Microcircuitry, EPFL, Lausanne .

EDUCATION

2003-2004: Postdoc, Laboratory of Neural Microcircuitry, Brain Mind Institute, Lausanne .

1999-2003: Doctoral studies, Dept. of Neurobiology, Weizmann Institute, Rehovot. PhD supervisor: Prof Henry Markram.

1998: MSc Studies in Neurobiology at the Weizmann Institute, Rehovot.

1994-97: BSc in Physics at the Hebrew University , Jerusalem .

SCHOLARSHIPS & AWARDS

2005: HFSP Long-Term fellowship

2003: BMI Prize for Research Excellence, EPFL, Lausanne .

1998-2002: The Weizmann Fellowship, scholarship for doctoral studies by the Feinberg Graduate School .

1997: European Crete Course for Computational Neuroscience.

1996: International summer laboratory course in Invertebrate Neuroethology in Jerusalem .

1994-7: “Amirim” BSc. scholarship program.

TEACHING & TUTORING

• - Tutoring and PhD Supervision of several doctoral students, brain mind Institute, EPFL, Lausanne  
• Cortical dynamics, The neocortical microcircuit, Multineuron patch-clamp technique, KI.
• Introduction to electrophysiology, Weizmann Institute.
• Introductory lab course for neuroscience, Weizmann Institute.
• Tutoring physics and math, Hebrew university, Jerusalem .

PUBLICATIONS

1. Silberberg, G, Kalisman, N*. & Markram, H. The Neocortical Microcircuit as a Tabula Rasa. PNAS, 2005, Jan 18;102(3):880-5.

2. Richardson M.J.E, Melamed O., Silberberg G., Markram H. & Gerstner W. Short-term synaptic plasticity orchestrates the response of pyramidal cells and interneurons to population bursts. Journal of Computational Neuroscience, 2005 Jun; 18(3): 323-331.

3. Melamed O., Silberberg G., Markram H., Gerstner W. & Richardson M.J.E. Subthreshold cross-correlations between cortical neurons. A reference model with static synapses. Neurocomputing, 65-66(2005), pp.685-690.

4. Markram H., Toledo-Rodriguez M., Wang Y., Gupta A., Silberberg G. & Wu CZ. (2004d) Interneurons of the Neocortical Inhibitory System. Nat Rev Neurosci. 2004 Oct;5(10):793-807

5. Wang Y., Toledo-Rodriguez M., Gupta A., Wu CZ., Silberberg, G., Luo JY. & Markram H. Anatomical, Physiological and Molecular Properties of Martinotti Cells in Rat Somatosensory Cortex. J Physiol. (Lond.) 2004 Nov 15;561(Pt 1):65-90.

6. Silberberg, G., Wu, CZ. & Markram, H. Synaptic Dynamics Control the Timing of Neuronal Excitation in the Activated Neocortical Microcircuit. J Physiol. (Lond.) 2004 Apr 1;556(Pt 1):19-27.

7. Silberberg, G., Bethge, M., Markram, H., Tsodyks, M., & Pawelzik, K. Realizing Rapid Population Rate Codes in Ensembles of Neocortical Neurons. J Neurophysiol. Feb. 2004, 91(2):704-9.

8 . Kalisman N. , G . Silberberg & H . Markram (2003). Deriving Physical Connectivity from Neuronal Morphology. Biological Cybernetics, (2003) 88(3):210-8.

9. Silberberg G, Gupta A & Markram H (2002). Stereotypy in Neocortical Microcircuits. Trends Neurosci. 2002 May;25(5):227-30.

10. Silberberg G, Grillner S, Lebeau FE, Maex R, Markram H.  Synaptic pathways in neural microcircuits. Trends Neurosci. 2005 Oct;28(10):541-51.

11. Grillner S, Markram H, De Schutter E, Silberberg G, Lebeau FE. Microcircuits in action - from CPGs to neocortex. Trends Neurosci. 2005 Oct;28(10):525-33.

BOOK CHAPTERS

1. Markram H, Luo X, Silberberg G, Toledo-Rodriguez M & Gupta A. The Neocortical Microcircuit Database (NMDB). In: Databasing the Brain, from Data to Knowledge (Koslow S.H. and Subramaniam S. eds.): Wiley Press, 2005.

2. Gupta A, Toledo-Rodriguez M, Silberberg G & Markram H (2003). “Interneuron Heterogeneity in the Neocortex”. In: Excitatory-Inhibitory Balance: Synapses, Circuits, Systems (Hensch TK, ed): Kluwer Academic Publishing.

 

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Last modified: 2009-06-02