Anna Josephson, M.D., Ph.D.
Josephson Laboratory
Research Focus
Our group is associated with the Lars Olson group where we mainly focus on the role of the Nogo nerve growth inhibitory system in:
- Spinal cord injury, were we aim to obtain post-injury protection and methods of reparation
- CNS plasticity, memory, aging and repair: we have recent data to suggest a key role for the Nogo receptor in the formation of life-long memories
- The development of Alzheimer's disease where we study the role of the Nogo system in the formation of amyloidal plaque
The aims of our studies are to advance the understanding of the Nogo signalling system in health and disease focusing on gene activity regulation and behavioural indications.
Selected Publications
Recovery from spinal cord injury differs between rat strains in a major histocompatibility complex-independent manner.
European Journal of Neuroscience 26: 1118-1127, 2007
Neuronal activity-induced regulation of Lingo-1.
Neuroreport 15: 2397-400, 2004
Selective decline of Nogo mRNA in the aging brain.
Neuroreport 17: 913-916, 2006
Activity-induced and developmental downregulation of the Nogo receptor.
Cell Tissue Research 311: 333-342, 2003
Nogo-receptor gene activity: cellular localization and developmental regulation of mRNA in mice and humans.
Journal of Comparative Neurology 453: 292-304, 2002
MED NORD--A tool for measuring medical students' well-being and study orientations.
Medical Teaching 30: 72-79, 2008
How do medical teachers address the problem of transfer?
Advancees in Health Science Education Theory and Practice Jan 3, 2007
Neurosurgeon, Associate Professor Anna Josephson
- Work:
- 08-524 870 72
- Fax:
- 08-32 37 42
- E-mail:
Karolinska Institutet
Retzius väg 8
S-17177 Stockholm, Sweden
