Lisette Graae1, Silvia Paddock2, and Andrea Carmine Belin1
1 Department of Neuroscience, Karolinska Institutet, Retzius väg 8, 171 77 Stockholm
2 Rose Li and Associates, Inc., Bethesda, MD, USA
ReMo-SNPs is a computational program developed to aid researchers in the process of selecting functional SNPs in the human genome for association analyses in user-specified regions and/or motifs genome-wide. The output data can be directly used in a following association study.
The user defines which human genomic regions and/or motifs the program should search through. In our example we have used experimentally validated transcription factor binding regions and in silico identified binding motifs. However, the flexibility of the ReMo-SNPs program makes it easy to adapt to different projects and research questions without limitation to transcription factors.