Homepage - Andreas Klaus
Andreas.Klaus@ki.se
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Andreas Klaus
I am currently a PhD student at the Department of Neuroscience, Karolinska Institute, Stockholm. My supervisors are Jeanette Hellgren-Kotaleski (KI, KTH, Stockholm), Dietmar Plenz (NIMH, Bethesda), and Gilad Silberberg (KI, Stockholm).
The aim of my research is to gain a better understanding of the striatal gating mechanisms by means of detailed computational modeling and experimental measurements in organotypic triple cultures (cortex, striatum, and substantia nigra). The striatum is the main input stage of the basal ganglia system, which makes it interesting to study. (Click
here for an introduction to the basal ganglia system.)
Contact
Andreas Klaus
Department of Neuroscience
Karolinska Institute
Retzius väg 8
171 77 Stockholm, Sweden
Email: Andreas.Klaus@ki.se
or
Porter Neuroscience Research Center
National Institute of Mental Health
Building 35, Room 3A-107
Bethesda, MD, 20892, USA
Phone: +1 (301) 451 2886
Email: KlausAM@mail.nih.gov
Research interests and methods
- Striatal gating of cortical input
- Neuronal modeling
- Optimization techniques
- Multi-electrode measurements of local field activity
- High performance computing
See also:
Journal publications
Klaus A., Warrant E.J. (2009): Optimum spatiotemporal receptive fields for vision in dim light. Journal of Vision, 9(4):18: 1-16. [Abstract], [PDF], doi:10.1167/9.4.18
Herrmann C.S., Klaus A. (2004): Autapse turns neuron into oscillator. International Journal of Bifurcation and Chaos, 14(2): 623-633. [PDF]
Technical reports
Hackbusch W., Khoromskij B.N., Klaus A. (2005): Approximation of functions by exponential sums based on the Newton-type optimisation, Technical report 3/2005, Max-Planck-Institut für Mathematik in den Naturwissenschaften. [Abstract], [PDF]
Abstracts
Klaus A., Hjorth J., and Hellgren-Kotaleski J. (2009): The influence of stuttering properties for firing activity in pairs of electrically coupled striatal fast-spiking interneurons Frontiers in Neuroinformatics. Conference Abstract: 2nd INCF Congress of Neuroinformatics. [Abstract].
Klaus A., Hjorth J., and Hellgren-Kotaleski J. (2009): The influence of subthreshold membrane potential oscillations and GABAergic input on firing activity in striatal fast-spiking neurons Eighteenth Annual Computational Neuroscience Meeting: CNS*2009, Berlin. [Abstract], [PDF].
Klaus A., Hellgren-Kotaleski J. (2008): Synchronization effects between striatal fast-spiking interneurons forming networks with different topologies. Frontiers in Neuroinformatics. Conference Abstract: Neuroinformatics 2008. doi:10.3389/conf.neuro.11.2008.01.041